Case Study On

A. A farmer started having difficulty breathing and vigour cramping, with take place muscle control and some rigidity. He recalled that the symptoms started soon after he started using a new pesticide in the fields. The magical spell of normal muscle physiology at the cellular level. 1.A beat mainstay neuron wall sockets acetylcholine (Ach) molecules as a transmitter. 2.Ach diffuses from the centre goal and attaches to a protein receptor in the muscle cell membrane. 3.The Ach receptors be randy to open sodium ion (Na+) gates in the membrane, and Na+ rushes in across the membrane. 4.This depolarizes the membrane and causes a proceed well-nigh of calcium ions (Ca2+) from the cells sarcoplasmic second stomach (SR). 5.Ca2+ attaches to troponin protein, which is on the actin, and causes the actin to rotate and move the interfering tropomyosin out of the track (tropomyosin sits in its resting position and blocks the interaction of actin with myosin, the main mus cle proteins). 6. at once tropomyosin is moved, actin and myosin interact. Myosin has the ATPase enzyme to release the dynamism needed to contract. 7.The pivoting heads of the myosin pulls the actin along from opposite sides, where the actin units atomic number 18 anchored. This shortens the muscle as individual units (sarcomeres) are contracted. 8.

Muscle concretion continues for the short goal of time that the Ach is bound to the receptor, and continued release of Ach by the nerve cell can keep the muscle contracting (tetany = a tetanic contraction). A single release of Ach would cause a twitch 9.Becau se to regulate muscle contractions, the Ach ! is chop-chop degraded by the enzyme acetylcholine esterase, and muscles relax as all the activities above revert buttocks to their original state (K+ moves out to repolarize the membrane). In normal movements, our muscles are stimulated many times in quick season to achieve a smooth, sustained contraction. attached motor units are stimulated asynchronously at a absolute frequency that will produce...If you want to get a full essay, tack together it on our website: OrderCustomPaper.com

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